Research & Development

We provide beauty and health produced from dermatology, dietetics and beauty treatment technology.

Development Process

BLOOM CLASSIC gives the greatest attention to what customers really need, manufacturing high-level, high-quality products with an integrated system from planning through to production.


1.Prescription development, prototype production

Formulation Room

Prototyping is repeated in order to develop products that satisfy customer requests. We also search for new raw material.

Scales

Scales are used to measure the weight of reagents, etc.
Measurements can be made to 0.001g.

Mixer

Blends liquids evenly. Highly viscous liquids can also be mixed.

Vacuum emulsification machine

Mixes water-based and oil-based raw materials to roduce emulsion. The addition of bubbles is prevented by forming a vacuum inside a doublelayered.

Rotary evaporator/freeze-dryer

Mainly used for concentration of extracts, etc. The rotary evaporators (left) warms a flask to vaporize solvent and removes extracts, while the freeze-dryer (right) freezes and then leaves in a vacuum state to get rid of the solvent.

Viscosity, solidity, moisture and pH meters

These meters are used to measure viscosity, solidity, moisture and pH, and we confirm whether the quality of the trial product is that which is sought by the customer.


2.Confirmation of effectiveness and safety

Cultivation Room

Human cultured cells are used to confirm the effectiveness and safety of trial product.

Clean bench

An air curtain is in place to prevent contamination by dust or germs, and work is conducted in a sterilised state.

Incubator

Cells are cultivated and their progress is monitored inside this incubator set with an environment preferred by cells.

Handstand microscope

This microscope checks the state of the cultivated cells.

Centrifugal machine

Centrifugal force is used for filtration and to separate liquids from solids.

Liquid nitrogen freezer and storage container

Cells can be kept for a long time when stored in liquid nitrogen.


3.Confirmation of mixed ingredients and function

Analysis Room

Checks what kinds of mixed ingredients are contained in the product.

High-speed liquid chromatograph

Accurately measures the ingredients contained in liquid as well as their concentration.

Analytical scales

Can measure to an accuracy of 0.00001g. Mainly used in analysis of high-speed liquid chromatograph, etc.

Spectrophotometer

Mainly used for concentration of extracts, etc.
The rotary evaporators (left) warms a flask to vaporize solvent and removes extracts, while the freeze-dryer (right) freezes and then leaves in a vacuum state to get rid of the solvent.

Microplate reader

Quantifies the effects on cells, etc. from shading when cells have been stained with reagents, etc.


4.Evaluations in human skin〈final confirmation of effectiveness and safety〉

Skin Monitor Room

The effectiveness and safety of final trial products is checked in humans using various machines.

Replica analysis information

Skin replicas are collected, and skin conditions such as wrinkles, textures and pores are analyzed.

Microscope

After staining the collected keratin, conditions are analyzed under a microscope.

Patch test

Products are pplied directly to human skin, verdicts are made by specialist dermatologists, and stimulation of the skin is researched.

Robo skin analyze

The face as a whole undergoes image processing, and the numbers and areas where acne or spots are at present (or are predicted to occur in future) can be estimated as numerical values.

Multi-probe adapte

Measures skin moisture, greasiness, elasticity, pH, blushes, melanin, and moisture transpiration.


5.Confirmation of stability

Environmental Experiment Room

Stability is confirmed in order to provide quality assurance of trial products finished exactly to satisfy customer requests for a period of three years.

Incubator

Acceleration experiments are performed by leaving the trial product at temperatures of 5℃, 40℃, 45℃, and 55℃. Changes in condition/quality are checked through observations made at regular intervals over a period of six months.